Vertebroplasty for acute painful osteoporotic vertebral compression fractures: An update.

2019-12

Lamanna, Anthony

Maingard, Julian

Kok, Hong Kuan

Ranatunga, Dinesh

Looby, Seamus T

Brennan, Paul

Chua, Michelle

Owen, Andrew

Brooks, Duncan Mark

Chandra, Ronil V

Asadi, Hamed

osteoporosis

osteoporotic fractures

vertebral compression fractures

vertebral fractures

vertebroplasty

Journal Article

0000-0003-0705-2252

0000-0001-8958-2411

10.1111/1754-9485.12900

Vertebral compression fractures (VCFs) are a common cause of back pain and disability and are usually osteoporotic in nature. Therapy aims to adequately control pain and allow early mobilisation and return of function while preventing additional fractures. A proportion of patients do not achieve adequate pain relief using conservative measures alone. Unwanted adverse effects from medications may also ensue. Vertebroplasty represents an alternative treatment option for VCFs. Patients with acute VCFs (≤6 weeks old) may gain the most benefit from vertebroplasty as healed fractures are not as amenable to cement injection. High-quality studies have reported conflicting results regarding the use of vertebroplasty in the treatment of acute VCFs. Despite high-quality evidence, varying study designs and heterogenous patient cohorts make interpretation of this data difficult. Only one sham-controlled randomised controlled trial (RCT) has evaluated vertebroplasty exclusively in patients with acute VCFs, reporting favourable results. Pooled data from RCTs also suggest vertebroplasty to be safe. This article provides a concise and critical review of the current literature regarding vertebroplasty for the treatment of acute VCFs.

link

Journal of Medical Imaging and Radiation Oncology 2019; 63(6): 779-785

Journal of Medical Imaging and Radiation Oncology