Please use this identifier to cite or link to this item:
Title: Compliance in patients with dietary hyperoxaluria: A cohort study and systematic review.
Austin Authors: Hennessey, Derek B;Kinnear, Ned J;Rice, Gilbert;Curry, David;Woolsey, Siobhan;Duggan, Brian
Affiliation: Department of Urology, Ulster Hospital, Belfast, United Kingdom
Department of Urology, Austin Health, Heidelberg, Victoria, Australia
Department of Urology, Belfast City Hospital, Belfast, United Kingdom
Issue Date: Apr-2019 2018-03-29
Publication information: Asian journal of urology 2019; 6(2): 200-207
Abstract: Hyperoxaluria leads to calcium oxalate crystal formation and subsequent urolithiasis. This study aims to analyse the effect of treatment compliance in hyperoxaluria, firstly by analysis of patients with non-primary hyperoxaluria and secondly via systematic review in patients with any hyperoxaluria. In a retrospective cohort study, adults with non-primary hyperoxaluria managed with dietary counselling in 2013 were enrolled. Twenty-four-hour (24 h) urine collections initially and at 6 months were obtained. Compliance was assessed by self-reported dietary compliance and 24 h urinary volume >2 L. Patients were followed for 24 months. Primary outcomes were urinary oxalate and calcium 24 h load at 6 months, and urolithiasis-related procedural rates at 24 months. A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compatible systematic review of compliance among hyperoxaluric patients was performed. In the cohort study, of 19 eligible patients (4 female) with median age 52 years, 10 (53%) were considered compliant. Compared with the non-compliant group, these patients had significantly increased subsequent 24 h urinary volume (2250 mL vs. 1600 mL; p = 0.008) and lower procedural rates (10% vs. 56%; p = 0.033). Subsequent 24 h urinary oxalate load was non-significantly lower in compliant patients. Systematic review regarding compliance in hyperoxaluric patients revealed five studies. Only one utilised dietary counselling or analysed compliant vs. non-compliant patients, finding no difference. None examined the effect of compliance on procedural rates. Hyperoxaluria is an important cause of recurrent urolithiasis. Increasing fluid intake and reducing dietary oxalate reduce the risk of operative intervention and remain fundamental to the treatment of hyperoxaluria.
DOI: 10.1016/j.ajur.2018.03.002
ORCID: 0000-0002-7833-2537
PubMed URL: 31061807
ISSN: 2214-3882
Type: Journal Article
Subjects: Hyperoxaluria
Metabolic stone disease
Recurrent stone former
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on Nov 27, 2022

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.