Please use this identifier to cite or link to this item:
Title: Pseudomonas meningoencephalitis masquerading as a stroke in a patient on tocilizumab.
Austin Authors: Williams, Cameron J;Foote, Andrew;Choi, Philip
Affiliation: Royal Melbourne Hospital, Parkville, Victoria, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Issue Date: 28-Jan-2019
Date: 2019-01-28
Publication information: BMJ Case Reports 2019; 12(1): bcr-2018-227296
Abstract: A previously high-functioning woman presents with clinical and CT features of a subacute ischaemic stroke. Her medical history is relevant for refractory giant cell arteritis on long-term high-dose prednisolone and recent commencement of tocilizumab (interleukin-6 monoclonal antibody). The potential for stroke mimic is considered and a magnetic resonance brain scan is requested. She rapidly deteriorates within 24 hours of admission and unexpectantly dies. An autopsy reveals that she has bilateral pulmonary emboli with lower limb deep vein thrombosis and Pseudomonas meningoencephalitis with frank pus on the brain. We discuss the potential risks of immunosuppression and the role of imaging in the diagnosis of stroke.
DOI: 10.1136/bcr-2018-227296
ORCID: 0000-0003-4952-8896
Journal: BMJ Case Reports
PubMed URL: 30696642
Type: Journal Article
Subjects: biological agents
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on May 30, 2024

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.