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Title: A Comparative Review of Mixed Mammary Tumors in Mammals.
Austin Authors: Saad, Eman S A;Lam, Jacqueline S Y;Al-Khan, Awf A;Tayebi, Mourad;Day, Michael J;Richardson, Samantha J;Danks, Janine A
Affiliation: School of Veterinary and Life Sciences, Murdoch University, Western Australia, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia
Laverty Pathology, Macquarie Park, Sydney, Australia
School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia
Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: Jun-2019 2018-11-28
Publication information: Journal of mammary gland biology and neoplasia 2019; 24(2): 125-137
Abstract: Mixed tumors are characterized by the histological identification of two or more cell types. Commonly, a mixture of epithelial and myoepithelial cells is included in abundant stroma, which can consist of myxoid, chondroid or bony matrices. Spontaneously arising mixed tumors are rare lesions in the human breast but are common in human salivary glands and canine mammary glands. Subtle histopathological characteristics and overlapping attributes of malignant lesions with other benign lesions can lead to a diagnostic challenge. Mixed tumors can present as benign or malignant. While malignant mixed tumors are quite rare in the human breast they have a poor prognosis. Benign mixed mammary tumors occur more frequently in female dogs than in humans and are usually associated with a good prognosis. This review will provide a comprehensive overview of mixed mammary tumors, across various mammalian species.
DOI: 10.1007/s10911-018-9422-2
ORCID: 0000-0002-2789-3449
Journal: Journal of mammary gland biology and neoplasia
PubMed URL: 30488318
Type: Journal Article
Subjects: Carcinomas in benign mixed tumors
Epithelial element
Mesenchymal element
Metaplastic breast cancers
Mixed mammary tumors
Appears in Collections:Journal articles

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