Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/19521
Title: qSOFA as predictor of mortality and prolonged ICU admission in Emergency Department patients with suspected infection.
Austin Authors: Canet, Emmanuel;Taylor, David McD ;Khor, Richard ;Krishnan, Vivek;Bellomo, Rinaldo 
Affiliation: MKM Health, South Yarra, Melbourne, Victoria, Australia
Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
Olivia Newton-John Cancer Wellness and Research Centre, Austin Health, Heidelberg, Victoria, Australia
Department of Radiation Oncology, Austin Health, Heidelberg, Victoria, Australia
Sir Peter MacCallum Department of Oncology, Melbourne University, Victoria, Australia
Department of Emergency Medicine, Austin Health, Heidelberg, Victoria, Australia
Data Analytics Research and Evaluation (DARE) Centre, Austin Health and The University of Melbourne, Heidelberg, Victoria, Australia
School of Medicine, The University of Melbourne, Parkville, Melbourne, Victoria, Australia
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Issue Date: 21-Aug-2018
metadata.dc.date: 2018-08-21
Publication information: Journal of Critical Care 2018; 48: 118-123
Abstract: We assessed the quick Sequential Organ Failure Assessment (qSOFA) score as a predictor of in-hospital mortality or prolonged ICU stay in Emergency Department (ED) patients with suspected infection. We measured qSOFA in a cohort of 11,205 ED patients with suspected infection. The primary outcome was in-hospital mortality and/or ICU stay ≥3 days. The qSOFA score was positive in 2429 (21.7%) patients. In-hospital mortality, and in-hospital mortality or ICU stay ≥3 days were 12.8% and 17.2% respectively for qSOFA positive patients vs 2.2% and 4.2% for qSOFA negative patients (p < .0001). For the prediction of in-hospital mortality, a positive qSOFA had a positive predictive value (PPV) of 13% (95% CI, 11-14) and a negative predictive value (NPV) of 98% (95% CI, 97-98). For the prediction of in-hospital mortality or ICU stay ≥3 days, the PPV and NPV of a positive qSOFA were 17% (95% CI, 16-19) and 96 (95% CI, 95-96), respectively. Among ED patients with suspected infection, a positive qSOFA identified those at much greater risk of mortality and longer ICU stay.
URI: http://ahro.austin.org.au/austinjspui/handle/1/19521
DOI: 10.1016/j.jcrc.2018.08.022
ORCID: 0000-0002-1650-8939
0000-0002-8986-9997
PubMed URL: 30176527
Type: Journal Article
Subjects: Emergency department
Infection
Intensive Care Unit
Mortality
Sepsis
qSOFA
Appears in Collections:Journal articles

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