Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/19020
Title: Chromobacterium violaceum infection in chronic granulomatous disease: a case report and review of the literature.
Austin Authors: Meher-Homji, Zaal;Mangalore, Rekha Pai;Johnson, Paul D R ;Chua, Kyra Y L 
Affiliation: Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Department of Microbiology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 31-Jan-2017
metadata.dc.date: 2017-01
Publication information: JMM case reports 2017; 4(1): e005084
Abstract: Introduction.Chromobacterium violaceum is an opportunistic human pathogen, associated with significant mortality, and has been reported in patients with chronic granulomatous disease (CGD), a genetic condition causing impaired phagocytosis. Case presentation. A 28-year-old man with a history of CGD presented with fever, pharyngitis, cervical lymphadenopathy and internal jugular vein thrombosis, following travel to the rural Solomon Islands. C. violaceum was recovered from his blood. The patient recovered after treatment with meropenem and trimethoprim/sulfamethoxazole. Conclusion. To the best of our knowledge, this is the first case report of internal jugular vein thrombophlebitis (Lemierre's syndrome) caused by C. violaceum in a patient with CGD. A review of the literature demonstrated that the diagnosis of C. violaceum preceded the diagnosis of CGD in the majority of cases. This case emphasizes the importance of this organism in patients with CGD who live in or visit tropical areas.
URI: http://ahro.austin.org.au/austinjspui/handle/1/19020
DOI: 10.1099/jmmcr.0.005084
ORCID: 0000-0001-9873-7163
PubMed URL: 28348801
ISSN: 2053-3721
Type: Journal Article
Subjects: Chromobacterium violaceum
Lemierre's syndrome
meropenem
trimethoprim/sulfamethoxazole
Appears in Collections:Journal articles

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