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Title: Performance of an active inspired hypoxic guard.
Austin Authors: Ghijselings, Idris E;De Cooman, Sofie;Carette, Rik;Peyton, Philip J ;De Wolf, Andre M;Hendrickx, Jan F A
Affiliation: Department of Anesthesiology, Intensive Care and Pain Therapy, OLV Hospital, Aalst, Belgium
Department of Anesthesiology, Sint-Jan Clinic, Brussels, Belgium
Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
University of Melbourne, Melbourne, Australia
Issue Date: Feb-2016
Date: 2015-03-11
Publication information: Journal of clinical monitoring and computing 2016; 30(1): 63-8
Abstract: Current hypoxic guards systems fail to maintain the inspired O2 concentration (FIO2) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N2O or air). We examined the performance of the Maquet O2 Guard(®), a smart hypoxic guard that increases O2 delivery if an inspired hypoxic mixture is formed. After obtaining IRB approval and informed consent, 12 ASA I-II patients were enrolled. During anesthesia with sevoflurane in O2/air, the O2 Guard(®) was tested by administering O2/air at the following delivered hypoxic guard limits [expressed as (total FGF in L min(-1); FDO2 in %)] for 4 min each: [0.3;67], [0.4;50], [0.6;34], [0.8;25], [1.0;21], [1.2;21], [1.5;21], [2;21], [3;21], and [5;21]. The following data were collected: (1) time from FIO2 = 30 to 20 %; (2) time from FIO2 = 20 % to O2 Guard(®) activation; (3) time from O2 Guard(®) activation to FIO2 = 25 %; (4) FGF and FDO2 used by the O2 Guard. If SpO2 was <90 % for 10 s or longer at any time, the patient was excluded. Three patients were excluded for low SpO2. The incidence of FIO2 < 21 % was 100 % within the 1-2 L min(-1) FGF range. The O2 Guard(®) was activated within 20 s after FIO2 became 20 %, except in one patient where FIO2 oscillated between 20 and 21 %. FDO2 was increased to 60 % and FGF to 1 L min(-1) (the latter only if it was lower than 1 L min(-1) prior to activation of the O2 Guard). FIO2 increased to 25 % within 55 s after O2 Guard activation in all patients. The O2 Guard(®), an active inspired hypoxic guard, rapidly reverses and limits the duration of inspired hypoxic episodes when the delivered hypoxic guard fails to do so.
DOI: 10.1007/s10877-015-9684-9
Journal: Journal of clinical monitoring and computing
PubMed URL: 25757405
Type: Journal Article
Subjects: Hypoxia
Hypoxic guard system
Hypoxic mixtures
Machine standards
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