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Title: Improving the Recognition of, and Response to In-Hospital Sepsis.
Austin Authors: Chan, Peter;Peake, Sandra;Bellomo, Rinaldo ;Jones, Daryl A 
Affiliation: Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Intensive Care Unit, Austin Health, Heidelberg, Victoria, Australia
Western Hospital-Footscray, Footscray, Victoria, Australia
Department of Intensive Care Medicine, The Queen Elizabeth Hospital, Woodville, SA, Australia
Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: Jul-2016
Publication information: Current infectious disease reports 2016; 18(7): 20
Abstract: Sepsis is an important cause of patient morbidity and mortality worldwide. Although the associated mortality seems to be decreasing, approximately 20 % of patients with organ dysfunction die in hospital. Since 1991 diagnostic criteria for sepsis focused on the systemic inflammatory response syndrome (SIRS). However, the utility of such criteria has been questioned, and alternative criteria have recently been proposed. It is likely that administration of early appropriate antibiotics and resolution of shock reduce sepsis-associated mortality. Accordingly, strategies need to be developed to improve the early recognition of, and response to patients with sepsis. Such system approaches may include improved acquisition and documentation of vital signs, enhanced recognition of shock, and integration of laboratory and microbiological results using clinical informatics. Hospitals should have guidelines for escalating care of septic patients, antibiotics stewardship programs, and systems to audit morbidity and mortality associated with sepsis.
DOI: 10.1007/s11908-016-0528-7
ORCID: 0000-0002-1650-8939
PubMed URL: 27193917
ISSN: 1523-3847
Type: Journal Article
Subjects: Deteriorating patient
Early intervention
Rapid response team
Severe sepsis
Appears in Collections:Journal articles

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