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Title: Does perioperative ketamine have a role in the prevention of chronic postsurgical pain: the ROCKet trial.
Austin Authors: Schug, Stephan A;Peyton, Philip J 
Affiliation: Anaesthesiology and Pain Medicine, Medical School, The University of Western Australia, Crawley, WA, Australia
Anaesthesia, Perioperative and Pain Medicine Unit (APPMU), Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia
Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, WA, Australia
Issue Date: 6-Oct-2017
Date: 2017-11
Publication information: British journal of pain 2017; 11(4): 166-168
Abstract: Identifying operations and individuals with an increased risk of chronic postsurgical pain (CPSP) has led to significant interest in interventions with the potential to achieve primary prevention of this condition. Pharmacological prevention remains controversial with a Cochrane review identifying perioperative ketamine administration as the only intervention with possible benefit although, with only small, heterogeneous studies, the authors called for a large randomised controlled trial (RCT) to confirm the validity of this result. In response to these data, a group of researchers from Australia and Hong Kong designed the ROCKet trial - Reduction Of Chronic Post-surgical Pain with Ketamine, endorsed by the Australian and New Zealand College of Anaesthetists (ANZCA) Clinical Trials Network (CTN).
DOI: 10.1177/2049463717736076
Journal: British journal of pain
PubMed URL: 29123660
ISSN: 2049-4637
Type: Journal Article
Subjects: Ketamine
chronic postsurgical pain
clinical trial
pain management
Appears in Collections:Journal articles

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