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Title: The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.
Austin Authors: Trubiano, Jason A ;Stone, Cosby A;Grayson, M Lindsay ;Urbancic, Karen F ;Slavin, Monica A;Thursky, Karin A;Phillips, Elizabeth J
Affiliation: Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Centre for Improving Cancer Outcomes through Enhanced Infection Services, National Health and Medical Research Council Centre of Research Excellence, The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn
Department of Medicine, University of Melbourne, Parkville, Victoria, Australia
Department of Pharmacy, Austin Health, Heidelberg, Victoria, Australia
National Centre for Antimicrobial Stewardship, Royal Melbourne Hospital, Parkville, Victoria, Australia
Institute for Immunology & Infectious Diseases, Murdoch University, Murdoch, WA, Australia
Department of Medicine, Pathology, Microbiology, Immunology, Vanderbilt University Medical Center, Nashville, Tenn
Department of Pharmacology, Vanderbilt University Medical School, Nashville, Tenn
Issue Date: 2017 2017-08-23
Publication information: The journal of allergy and clinical immunology. In practice 2017; 5(6): 1532-1542
Abstract: Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies requires the engagement of key stakeholders such as allergists, immunologists, pharmacists, and infectious diseases physicians. To help address this burden of antibiotic allergy overlabeling, we review 3 key antibiotic allergy domains: (1) antibiotic allergy classification, (2) antibiotic cross-reactivity, and (3) multidisciplinary collaboration. We review the available evidence and research gaps of currently used adverse drug reaction classification systems, antibiotic allergy cross-reactivity, and current and future models of antibiotic allergy care.
DOI: 10.1016/j.jaip.2017.06.017
PubMed URL: 28843343
Type: Journal Article
Subjects: Antibiotic allergy
Antimicrobial allergy
Cephalosporin allergy
Penicillin allergy
Appears in Collections:Journal articles

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