Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/18106
Title: Postoperative renal dysfunction after noncardiac surgery.
Austin Authors: Vaara, Suvi T;Bellomo, Rinaldo 
Affiliation: Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
The University of Melbourne, Melbourne, Victoria, Australia
Issue Date: Oct-2017
Publication information: Current opinion in critical care 2017; 23(5): 440-446
Abstract: The narrative review aims to discuss recent results and important knowledge gaps regarding acute kidney injury (AKI) in postoperative patients undergone major noncardiac surgery. Postoperative AKI affects approximately one-fifth of patients after major surgery, but the incidence varies according to the type of surgery. Preexisting chronic kidney disease is a major risk factor for postoperative AKI. It carries a substantial risk for postoperative adverse outcomes, as well as long-term mortality and morbidity. To prevent postoperative AKI, avoiding intraoperative hypotension and hypoperfusion as well as nephrotoxic substances are important. Currently, no efficient pharmacotherapy for prevention or treatment of AKI is available. In general, goal-directed management protocols have reduced the incidence of postoperative AKI. Additionally, a restrictive fluid management regimen might reduce organ edema and be beneficial also for the kidney function. AKI is a frequent postoperative complication with a substantial risk for both short and long-term adverse events, and its incidence is likely to rise because of increasing major surgical procedures. Studies investigating better strategies to prevent and treat AKI in this population are urgently needed.
URI: http://ahro.austin.org.au/austinjspui/handle/1/18106
DOI: 10.1097/MCC.0000000000000439
ORCID: 0000-0002-1650-8939
PubMed URL: 28820797
Type: Journal Article
Appears in Collections:Journal articles

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