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Title: Sleeping tongue: current perspectives of genioglossus control in healthy individuals and patients with obstructive sleep apnea.
Austin Authors: Cori, Jennifer M ;O'Donoghue, Fergal J ;Jordan, Amy S 
Affiliation: Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australia
Department of Psychology, Melbourne School of Psychological Sciences, University of Melbourne, Parkville, Victoria, Australia
Department of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 15-Jun-2018 2018-06-15
Publication information: Nature and science of sleep 2018; 10: 169-179
Abstract: The focus of this review was on the genioglossus (GG) muscle and its role in maintaining upper airway patency in both healthy individuals and obstructive sleep apnea (OSA) patients. This review provided an overview of GG anatomy and GG control and function during both wakefulness and sleep in healthy individuals and in those with OSA. We reviewed evidence for the role of the GG in OSA pathogenesis and also highlighted abnormalities in GG morphology, responsiveness, tissue movement patterns and neurogenic control that may contribute to or result from OSA. We summarized the different methods for improving GG function and/or activity in OSA and their efficacy. In addition, we discussed the possibility that assessing the synergistic activation of multiple upper airway dilator muscles may provide greater insight into upper airway function and OSA pathogenesis, rather than assessing the GG in isolation.
DOI: 10.2147/NSS.S143296
ORCID: 0000-0001-5099-3184
PubMed URL: 29942169
ISSN: 1179-1608
Type: Journal Article
Subjects: airway collapsibility and sleep
airway obstruction
pharyngeal dilators
upper airway
Appears in Collections:Journal articles

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