Please use this identifier to cite or link to this item:
Title: Glycemic Control as Primary Prevention for Diabetic Kidney Disease.
Austin Authors: MacIsaac, Richard J;Jerums, George ;Ekinci, Elif I 
Affiliation: Department of Endocrinology & Diabetes, St Vincent's Hospital Melbourne, Australia
Department of Medicine, University of Melbourne, Victoria, Australia
Issue Date: Mar-2018
Publication information: Advances in Chronic Kidney Disease 2018; 25(2): 141-148
Abstract: Improving strategies to prevent the development and progression of CKD is a highly desirable outcome for all involved in the care of patients with diabetes. This is because CKD is a major factor contributing to morbidly and mortality in patients with diabetes. Furthermore, diabetes is the leading cause of ESRD in most developed countries. Although tight glucose control is now an established modality for preventing the development and progression of albuminuria, evidence is now accumulating to suggest that it can also ameliorate glomerular filtration rate loss and possibly progression to ESRD. These benefits of intensive glucose control appear to be most pronounced when applied to patients with the early stages of CKD. Recently, medications that belong to the sodium glucose cotransporter-type 2 inhibitor and the glucagon-like peptide-1 receptor analogue classes have been shown to reduce progression of CKD in patients with type 2 diabetes and relatively well-preserved kidney function. Here, we review the evidence from observational and interventional clinical studies that link good glucose control with the primary prevention of diabetic kidney disease with a focus on preventing early glomerular filtration rate loss.
DOI: 10.1053/j.ackd.2017.11.003
ORCID: 0000-0003-2372-395X
Journal: Advances in Chronic Kidney Disease
PubMed URL: 29580578
Type: Journal Article
Subjects: Chronic
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on Apr 12, 2024

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.