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Title: How antibiotic allergy labels may be harming our most vulnerable patients.
Austin Authors: Trubiano, Jason A ;Grayson, M Lindsay ;Thursky, Karin A;Phillips, Elizabeth J;Slavin, Monica A
Affiliation: Austin Health, Heidelberg, Victoria, Australia
Peter MacCallum Cancer Centre and National Centre for Infections in Cancer, Melbourne, Victoria, Australia
Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia
Issue Date: 18-Jun-2018
Publication information: Medical Journal of Australia 2018; 208(11): 469-470
Abstract: Antibiotic allergy labels are accumulated by various mechanisms and are often incorrectly self-reported or recorded. Incorrect antibiotic allergy labels frequently persist in community and hospital medical records throughout patients’ health care journeys, either with the phenotype unverified by clinicians or recorded as unknown.1,2 Among a cohort of older Australian general medical inpatients, we identified that 25% had a mismatch between their reported and recorded antibiotic allergy.3 Further, as an additional source of incorrect antibiotic allergy labels, patients with a true immunological basis for antibiotic allergy, such as immediate (IgE-mediated) reactions, may lose reactivity over time.4 Incorrect antibiotic allergy labels often prevent the use of appropriate narrow spectrum penicillin and targeted antibiotic therapies in both community and hospital practice, frequently among the patients most in need.4,5
DOI: 10.5694/mja17.00487
ORCID: 0000-0002-5111-6367
Journal: Medical Journal of Australia
PubMed URL: 29902399
Type: Journal Article
Subjects: Adverse drug reactions
Anti-infective agents
Drug resistance, microbial
Appears in Collections:Journal articles

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