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Title: Innovative STRoke Interactive Virtual thErapy (STRIVE) online platform for community-dwelling stroke survivors: a randomised controlled trial protocol.
Austin Authors: Johnson, Liam G ;Bird, Marie-Louise;Muthalib, Makii;Teo, Wei-Peng
Affiliation: Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria, Australia
EuroMov, University of Montpellier, Montpellier, France
Cognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Victoria, Australia
Stroke Division, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Heidelberg, Victoria, Australia
SilverLine Research Services, Brisbane, Australia
Faculty of Health Sciences, Australian Catholic University, Melbourne, Australia
Institute of Sport, Exercise and Active Living (ISEAL), Victoria University, Melbourne, Australia
Faculty of Health, School of Health Sciences, University of Tasmania, Launceston, Tasmania, Australia
Department of Physical Therapy, University of British Columbia and the Rehabilitation Research Program, GF Strong Rehabilitation Centre, University of British Columbia, Vancouver, Canada
Issue Date: 2018
Date: 2018
Publication information: BMJ Open 2018; 8(1): e018388
Abstract: The STRoke Interactive Virtual thErapy (STRIVE) intervention provides community-dwelling stroke survivors access to individualised, remotely supervised progressive exercise training via an online platform. This trial aims to determine the clinical efficacy of the STRIVE intervention and its effect on brain activity in community-dwelling stroke survivors. In a multisite, assessor-blinded randomised controlled trial, 60 stroke survivors >3 months poststroke with mild-to-moderate upper extremity impairment will be recruited and equally randomised by location (Melbourne, Victoria or Launceston, Tasmania) to receive 8 weeks of virtual therapy (VT) at a local exercise training facility or usual care. Participants allocated to VT will perform 3-5 upper limb exercises individualised to their impairment severity and preference, while participants allocated to usual care will be asked to maintain their usual daily activities. The primary outcome measures will be upper limb motor function and impairment, which will be assessed using the Action Research Arm Test and Upper Extremity Fugl-Meyer, respectively. Secondary outcome measures include upper extremity function and spasticity, as measured by the box and block test and Modified AshworthScale, respectively, and task-related changes in bilateral sensorimotor cortex haemodynamics during hand reaching and wrist extension movements as measured by functional near-infrared spectroscopy. Quality of life will be measured using theEuro-Quality of Life-5 Dimension-5 LevelScale, and theMotor Activity Log-28will be used to measure use of the hemiparetic arm. All measures will be assessed at baseline and immediately postintervention. The study was approved by the Deakin University Human Research Ethics Committee in May 2017 (No. 2017-087). The results will be disseminated in peer-reviewed journals and presented at major international stroke meetings. ACTRN12617000745347; Pre-results.
DOI: 10.1136/bmjopen-2017-018388
ORCID: 0000-0002-4916-049X
Journal: BMJ Open
PubMed URL: 29317414
Type: Journal Article
Subjects: chronic Stroke
community-based rehabilitation
virtual gaming
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