Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/17188
Title: | Does Fluid Type and Amount Affect Kidney Function in Critical Illness? | Austin Authors: | Glassford, Neil J;Bellomo, Rinaldo | Affiliation: | Intensive Care Unit, Austin Health, Heidelberg, Victoria, Australia Department of Epidemiology and Preventive Medicine, Monash University, Australian and New Zealand Intensive Care Research Centre, Melbourne, Victoria, Australia School of Medicine, The University of Melbourne, VIC 3010, Australia |
Issue Date: | Apr-2018 | Date: | 2018-02-03 | Publication information: | Critical care clinics 2018; 34(2): 279-298 | Abstract: | Acute kidney injury (AKI) is common, although commonly used clinical diagnostic markers are imperfect. Intravenous fluid administration remains a cornerstone of therapy worldwide, but there is minimal evidence of efficacy for the use of fluid bolus therapy outside of specific circumstances, and emerging evidence associates fluid accumulation with worse renal outcomes and even increased mortality among critically ill patients. Artificial colloid solutions have been associated with harm, and chloride-rich solutions may adversely affect renal function. Large trials to provide guidance regarding the optimal fluid choices to prevent or ameliorate AKI, and promote renal recovery, are urgently required. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/17188 | DOI: | 10.1016/j.ccc.2017.12.006 | ORCID: | 0000-0002-1650-8939 | Journal: | Critical care clinics | PubMed URL: | 29482907 | Type: | Journal Article | Subjects: | Acute kidney injury Albumin Balanced solution Colloid Crystalloid Hydroxyethyl starch Intravenous fluid therapy Succinylated gelatin |
Appears in Collections: | Journal articles |
Show full item record
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.