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Title: Ureteral intramural metastatic deposit of prostate cancer with ureteric obstruction.
Austin Authors: Pascoe, Claire;Manning, Todd G ;Wetherell, David ;Lawrentschuk, Nathan
Affiliation: Department of Urology, Austin Health, Heidelberg, Victoria, Australia
Young Urology Researchers Organisation (YURO), Melbourne, Victoria, Australia
Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Issue Date: 6-Jan-2018
Date: 2018-01-06
Publication information: BMJ Case Reports 2018; 2018: bcr-2017-222480
Abstract: True metastatic ureteric lesions are exceptionally rare when sourced from any primary tumour. Primary prostatic cancer metastasis to the ureter is understandably even more atypical with very few cases reported in current literature. True intramural ureteric metastatic disease deposited from prostate cancer is an even rarer occurrence. We present a case of a man in his mid-60s with left-sided hydronephrosis in the setting of biochemical recurrence of Gleason 9 prostate cancer. Initially misdiagnosed as obstruction secondary to mass effect from a large trigonal lesion, subsequent investigation revealed solid intramural metastatic deposit of prostate primary tumour in the distal ureter. We detail current hypotheses regarding the subsequent pathophysiology of the disease and its common clinical presentations. Our case highlights that prostatic metastasis should be considered as a differential in coexisting prostate cancer and ureteric obstruction despite its low incidence.
DOI: 10.1136/bcr-2017-222480
ORCID: 0000-0001-5609-3769
Journal: BMJ Case Reports
PubMed URL: 29306855
PubMed URL:
Type: Journal Article
Subjects: prostate
surgical oncology
urological surgery
Appears in Collections:Journal articles

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