Austin Health

Title
Relationship between Urinary Sodium-to-Potassium Ratio and Ambulatory Blood Pressure in Patients with Diabetes Mellitus
Publication Date
2018-01
Author(s)
Libianto, Renata
Moran, John
O'Callaghan, Christopher J
Baqar, Sara
Chen, Angela X
Baker, Scott T
Clarke, Michelle V
Macisaac, Richard J
Jerums, George
Ekinci, Elif I
Subject
ambulatory blood pressure
diabetes
potassium
sodium
urinary electrolytes
Type of document
Journal Article
OrcId
0000-0003-2372-395X
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DOI
10.1111/1440-1681.12852
Abstract
Previous studies investigating the relationship between sodium intake and blood pressure have mostly relied on dietary recall and clinic blood pressure measurement. In this cross-sectional study, we aimed to investigate the relationship between 24h urinary sodium and potassium excretion, and their ratio, with 24h ambulatory blood pressure parameters including nocturnal blood pressure dipping in patients with type 1 and 2 diabetes. We report that in 116 patients with diabetes, systolic blood pressure was significantly predicted by the time of day, age, the interaction between dipping status with time, and 24h urinary sodium-to-potassium ratio (R2 =0.83) with a relative contribution of 53%, 21%, 20% and 6%, respectively. However, there was no interaction between urinary sodium-to-potassium ratio and dipping status.
Link
Citation
Clinical and Experimental Pharmacology and Physiology 2018; 45(1): 94-97
Jornal Title
Clinical and Experimental Pharmacology and Physiology

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