Please use this identifier to cite or link to this item:
Title: Relationship between Urinary Sodium-to-Potassium Ratio and Ambulatory Blood Pressure in Patients with Diabetes Mellitus
Austin Authors: Libianto, Renata;Moran, John;O'Callaghan, Christopher J ;Baqar, Sara;Chen, Angela X;Baker, Scott T ;Clarke, Michelle V;Macisaac, Richard J;Jerums, George ;Ekinci, Elif I 
Affiliation: Medicine (University of Melbourne)
Intensive Care Unit, Queen Elizabeth Hospital, Adelaide, SA, Australia
Clinical Pharmacology and Therapeutics
Department of Endocrinology, Flinders Medical Centre, Adelaide, SA, Australia
Department of Endocrinology and Diabetes, St Vincent's Hospital Melbourne, Melbourne, Victoria, Australia
Menzies School of Health Research, Darwin, NT, Australia
Issue Date: Jan-2018
Date: 2017-09-16
Publication information: Clinical and Experimental Pharmacology and Physiology 2018; 45(1): 94-97
Abstract: Previous studies investigating the relationship between sodium intake and blood pressure have mostly relied on dietary recall and clinic blood pressure measurement. In this cross-sectional study, we aimed to investigate the relationship between 24h urinary sodium and potassium excretion, and their ratio, with 24h ambulatory blood pressure parameters including nocturnal blood pressure dipping in patients with type 1 and 2 diabetes. We report that in 116 patients with diabetes, systolic blood pressure was significantly predicted by the time of day, age, the interaction between dipping status with time, and 24h urinary sodium-to-potassium ratio (R2 =0.83) with a relative contribution of 53%, 21%, 20% and 6%, respectively. However, there was no interaction between urinary sodium-to-potassium ratio and dipping status.
DOI: 10.1111/1440-1681.12852
ORCID: 0000-0003-2372-395X
Journal: Clinical and Experimental Pharmacology and Physiology
PubMed URL:
Type: Journal Article
Subjects: ambulatory blood pressure
urinary electrolytes
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on May 22, 2024

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.