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Title: Prevalence of obstructive sleep apnea in the general population: a systematic review
Austin Authors: Senaratna, Chamara V;Perret, Jennifer L ;Lodge, Caroline J;Lowe, Adrian J;Campbell, Brittany E;Matheson, Melanie C;Hamilton, Garun S;Dharmagem, Shyamali C
Affiliation: Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australia
School of Population and Global Health, The University of Melbourne, Melbourne, Australia
Department of Community Medicine, University of Sri Jayewardenepura, Nugegoda, Sri Lanka
Department of Lung and Sleep Medicine, Monash Health, Clayton, Australia
School of Clinical Sciences, Monash University, Clayton, Australia
Issue Date: Aug-2017 2016-07-18
Publication information: Sleep Medicine Reviews 2017; 34: 70-81
Abstract: With this systematic review we aimed to determine the prevalence of obstructive sleep apnea (OSA) in adults in the general population and how it varied between population sub-groups. Twenty-four studies out of 3807 found by systematically searching PubMed and Embase databases were included in this review. Substantial methodological heterogeneity in population prevalence studies has caused a wide variation in the reported prevalence, which, in general, is high. At ≥5 events/h apnea-hypopnea index (AHI), the overall population prevalence ranged from 9% to 38% and was higher in men. It increased with increasing age and, in some elderly groups, was as high as 90% in men and 78% in women. At ≥15 events/h AHI, the prevalence in the general adult population ranged from 6% to 17%, being as high as 49% in the advanced ages. OSA prevalence was also greater in obese men and women. This systematic review of the overall body of evidence confirms that advancing age, male sex, and higher body-mass index increase OSA prevalence. The need to a) consider OSA as having a continuum in the general population and b) generate consensus on methodology and diagnostic threshold to define OSA so that the prevalence of OSA can be validly compared across regions and countries, and within age-/sex-specific subgroups, is highlighted.
DOI: 10.1016/j.smrv.2016.07.002
PubMed URL:
Type: Journal Article
Subjects: Age
Body-mass index
General population
Obstructive sleep apnea (OSA)
Type of Clinical Study or Trial: Systematic Reviews
Appears in Collections:Journal articles

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