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Title: How should hyperferritinaemia be investigated and managed?
Austin Authors: Ong, Sim Y;Nicoll, Amanda J;Delatycki, Martin B 
Affiliation: Bruce Lefroy Centre, Murdoch Childrens Research Institute, Flemington Road, Parkville, Victoria, Australia
The University of Melbourne, Parkville, Victoria, Australia
Department of Gastroenterology and Hepatology, Royal Melbourne Hospital, Parkville, Victoria, Australia
Clinical Genetics, Austin Health, Heidelberg, Victoria, Australia
Department of Gastroenterology, Eastern Health, Box Hill, Victoria, Australia
Monash University, Clayton, Victoria, Australia
Issue Date: Sep-2016 2016-06-23
Publication information: European Journal of Internal Medicine 2016; 33: 21-27
Abstract: Hyperferritinaemia is commonly found in clinical practice. In assessing the cause of hyperferritinaemia, it is important to identify if there is true iron overload or not as hyperferritinaemia may be seen in other conditions such as excess alcohol intake, inflammation and non-alcoholic fatty liver disease. Assessment of whether the serum ferritin level is elevated or not should take into account body mass index, gender and age. This review article provides an overview of the different causes of hyperferritinaemia, differentiating those due to iron overload from those not due to iron overload, and provides an algorithm for clinicians to use in clinical practice to carry out appropriate investigations and management.
DOI: 10.1016/j.ejim.2016.05.014
PubMed URL:
Type: Journal Article
Subjects: Alcohol liver disease
Non-alcoholic fatty liver disease
Appears in Collections:Journal articles

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