Austin Health

Title
Immunotherapeutic strategies in antiphospholipid syndrome
Publication Date
2017-03
Author(s)
Hoi, Alberta Y
Ross, Laura
Day, Jessica
Buchanan, Russell R C
Subject
CAPS
antiphospholipid syndrome
therapeutic options
Type of document
Journal Article
DOI
10.1111/imj.13245
Abstract
Antiphospholipid syndrome (APS) is an autoimmune condition, characterized by the persistent presence of antiphospholipid antibodies (aPL) and either thrombosis or obstetric morbidity. The cornerstone of therapy is long-term anticoagulation to reduce morbidity and mortality; however, better understanding of the immunological pathways may direct us to develop future therapeutic strategies. We provide an overview of the current understanding of the immunopathogenesis of this perplexing condition and its associated morbidities and current evidence for some of the immunotherapeutic strategies.
Link
Citation
Internal Medicine Journal 2016; 47(3): 250-256
Jornal Title
Internal Medicine Journal

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