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https://ahro.austin.org.au/austinjspui/handle/1/13386| Title: | A multicentre double blind trial of fluoxetine versus amitriptyline in the treatment of depressive illness. | Austin Authors: | Judd, F K;Moore, K;Norman, Trevor R ;Burrows, Graham D;Gupta, R K;Parker, G | Affiliation: | University of Melbourne, Department of Psychiatry, Austin Hospital, Heidelberg, Victoria. | Issue Date: | 1-Mar-1993 | Publication information: | The Australian and New Zealand Journal of Psychiatry; 27(1): 49-55 | Abstract: | The antidepressant efficacy and side effect profile of a fixed dose of 20 mg/day of fluoxetine, a specific serotonin reuptake inhibitor, were compared to those of amitriptyline. Fifty-eight patients with DSM-III-R depression were randomly assigned to receive either fluoxetine or amitriptyline. Fifty-six patients (fluoxetine N = 23, amitriptyline N = 23) completed the 6 week study. Comparable antidepressant efficacy was demonstrated for the two drugs. Patients taking fluoxetine reported less side-effects than those taking amitriptyline. | Gov't Doc #: | 8481170 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/13386 | Journal: | The Australian and New Zealand Journal of Psychiatry | URL: | https://pubmed.ncbi.nlm.nih.gov/8481170 | Type: | Journal Article | Subjects: | Adult Amitriptyline.adverse effects.therapeutic use Depressive Disorder.drug therapy.psychology Double-Blind Method Female Fluoxetine.adverse effects.therapeutic use Humans Male Middle Aged Personality Inventory Suicide.prevention & control.psychology |
| Appears in Collections: | Journal articles |
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