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Title: A multicentre double blind trial of fluoxetine versus amitriptyline in the treatment of depressive illness.
Austin Authors: Judd, F K;Moore, K;Norman, Trevor R ;Burrows, Graham D;Gupta, R K;Parker, G
Affiliation: University of Melbourne, Department of Psychiatry, Austin Hospital, Heidelberg, Victoria.
Issue Date: 1-Mar-1993
Publication information: The Australian and New Zealand Journal of Psychiatry; 27(1): 49-55
Abstract: The antidepressant efficacy and side effect profile of a fixed dose of 20 mg/day of fluoxetine, a specific serotonin reuptake inhibitor, were compared to those of amitriptyline. Fifty-eight patients with DSM-III-R depression were randomly assigned to receive either fluoxetine or amitriptyline. Fifty-six patients (fluoxetine N = 23, amitriptyline N = 23) completed the 6 week study. Comparable antidepressant efficacy was demonstrated for the two drugs. Patients taking fluoxetine reported less side-effects than those taking amitriptyline.
Gov't Doc #: 8481170
Type: Journal Article
Subjects: Adult
Amitriptyline.adverse effects.therapeutic use
Depressive Disorder.drug therapy.psychology
Double-Blind Method
Fluoxetine.adverse effects.therapeutic use
Middle Aged
Personality Inventory
Suicide.prevention & control.psychology
Appears in Collections:Journal articles

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