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Title: Long-term drug treatment of panic disorder.
Austin Authors: Burrows, Graham D;Judd, F K;Norman, Trevor R 
Affiliation: Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 16-May-1993
Publication information: Journal of Psychiatric Research; 27 Suppl 1(): 111-25
Abstract: Drug treatment of panic disorder with benzodiazepines and antidepressants has been established as efficacious in the short-term (6-8 weeks). The efficacy of medications during long-term (i.e., continuous) treatment has not often been addressed and a review of the evidence is presented. Most data exists for the long-term effectiveness of benzodiazepines. Experience with the triazolobenzodiazepine, alprazolam, is reviewed together with some other high potency drugs, e.g., clonazepam. Tricyclic antidepressants are also effective in the long-term treatment of panic and the relevant studies are presented. Long-term efficacy for monoamine oxidase inhibitors is not as clearly established. The issue of relapse following drug withdrawal is addressed and some strategies for patient management in long-term therapy are discussed.
Gov't Doc #: 7908330
Type: Journal Article
Subjects: Anti-Anxiety Agents.adverse effects.therapeutic use
Antidepressive Agents.adverse effects.therapeutic use
Long-Term Care
Panic Disorder.drug therapy.psychology
Substance Withdrawal Syndrome.psychology
Appears in Collections:Journal articles

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