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Title: Effects of antihypertensive drugs on cardiovascular risk factors.
Austin Authors: Howes, L G;Louis, William J 
Affiliation: University of Melbourne, Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 1-Mar-1988
Publication information: Clinical and Experimental Pharmacology & Physiology; 15(3): 199-202
Abstract: 1. Large scale studies have failed to show a substantial benefit of antihypertensive therapy on the incidence of ischaemic heart disease. 2. This may be due to adverse effects of antihypertensive drugs on plasma lipoproteins or because of failure to adequately manage other risk factors for atherogenesis. 3. Hypercholesterolaemia is very common in patients receiving antihypertensive therapy, and is difficult to manage successfully using existing treatment strategies. 4. The achievement of a reduction in mortality and morbidity from ischaemic heart disease amongst hypertensive patients represents a major challenge. Success will probably depend upon the development of adequate methods of lowering plasma cholesterol levels.
Gov't Doc #: 3078275
Type: Journal Article
Subjects: Antihypertensive Agents.therapeutic use
Cardiovascular Diseases.drug therapy.physiopathology
Risk Factors
Appears in Collections:Journal articles

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