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Title: Platelet monoamine oxidase activity in patients with Huntington's disease.
Austin Authors: Norman, Trevor R ;Chiu, E;French, M A
Affiliation: Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 1-Jun-1987
Publication information: Clinical and Experimental Pharmacology & Physiology; 14(6): 547-50
Abstract: 1. Platelet monoamine oxidase (MAO) activity was investigated in 30 patients with Huntington's disease and compared with the activity in a control group. 2. Significantly elevated activity was found in the patients (P less than 0.05; t-test) when same sex contrasts were carried out to account for the well known influence of sex on MAO activity. 3. The mean MAO activity in male patients was 23.5 +/- 6.0 nmol/mg protein per h and female patients was 29.5 +/- 8.9 nmol/mg protein per h using tyramine as the substrate. 4. The possible influence of environmental factors on the results is discussed.
Gov't Doc #: 2960476
Type: Journal Article
Subjects: Adolescent
Blood Platelets.enzymology
Huntington Disease.enzymology
Middle Aged
Monoamine Oxidase.blood
Appears in Collections:Journal articles

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