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Title: Assessment and management of male androgen disorders: an update.
Austin Authors: Chan, Irene;Fui, Mark Ng Tang;Zajac, Jeffrey D ;Grossmann, Mathis 
Affiliation: MBBS, BMedSc, Endocrinology Advanced Trainee, Department of Endocrinology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 1-May-2014
Publication information: Australian Family Physician; 43(5): 277-82
Abstract: Male hypogonadism, caused by intrinsic pathology of the hypothalamic-pituitary-testicular (HPT) axis, is an under-diagnosed condition not to be missed. By contrast, late onset hypogonadism (LOH), due to functional suppression of the HPT axis from age-related comorbidities, may be less common than previously believed.This article outlines the aetiology, clinical features, investigation and management of male hypogonadism and discusses the more controversial area of LOH.Pathologically based hypogonadism is, after a thorough diagnostic work-up, treated with testosterone replacement therapy, unless fertility is desired. LOH with modest reductions in testosterone levels should primarily be managed by attention to lifestyle measures, especially weight loss, and optimisation of comorbidities. Clear treatment goals should be identified, and efficacy and safety should be monitored according to published clinical practice guidelines.
Gov't Doc #: 24791767
Type: Journal Article
Subjects: Age of Onset
Androgens.adverse effects.therapeutic use
Hormone Replacement Therapy.adverse effects
Hypogonadism.diagnosis.drug therapy.etiology.physiopathology
Hypothalamo-Hypophyseal System.physiopathology
Testosterone.adverse effects.therapeutic use
Appears in Collections:Journal articles

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