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Title: Utility of thromboelastography in managing acquired Factor VIII inhibitor associated massive haemorrhage.
Austin Authors: Fisher, C ;Mo, A ;Warrillow, Stephen J ;Smith, C;Jones, Daryl A 
Affiliation: Department of Intensive Care, Austin Hospital, Melbourne, Victoria.
Issue Date: 1-Nov-2013
Publication information: Anaesthesia and Intensive Care; 41(6): 799-803
Abstract: Disorders of clotting and coagulation are common in the intensive care unit. Diagnosis, treatment and monitoring of these disorders are traditionally based on conventional coagulation tests such as activated partial thromboplastin time (APTT) and international normalised ratio (INR). We present here a patient who developed massive postoperative haemorrhage secondary to an acquired factor VIII inhibitor. The case highlights the utility and sensitivity of thromboelastography (TEG) in the diagnosis of the condition and monitoring the response to therapy.
Gov't Doc #: 24180723
Journal: Anaesthesia and Intensive Care
Type: Journal Article
Subjects: acquired Factor VII inhibitor
Antifibrinolytic Agents.therapeutic use
Blood Coagulation Factors.therapeutic use
Blood Transfusion.methods
Factor VIIa.therapeutic use
Follow-Up Studies
Hematoma.complications.drug therapy
Hemophilia A.diagnosis.drug therapy
Middle Aged
Partial Thromboplastin Time.methods
Postoperative Hemorrhage.diagnosis.drug therapy
Radiography, Abdominal.methods
Recombinant Proteins.therapeutic use
Renal Insufficiency.complications.therapy
Renal Replacement Therapy.methods
Respiration, Artificial.methods
Respiratory Insufficiency.complications.therapy
Tomography, X-Ray Computed.methods
Tranexamic Acid.therapeutic use
Treatment Outcome
Appears in Collections:Journal articles

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