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Title: Amyloid imaging with PET in early Alzheimer disease diagnosis.
Austin Authors: Rowe, Christopher C ;Villemagne, Victor L 
Affiliation: Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia
University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 1-May-2013
Publication information: The Medical Clinics of North America; 97(3): 377-98
Abstract: In vivo imaging of amyloid-β (Aβ) with positron emission tomography has moved from the research arena into clinical practice. Clinicians working with cognitive decline and dementia must become familiar with its benefits and limitations. Amyloid imaging allows earlier diagnosis of Alzheimer disease and better differential diagnosis of dementia and provides prognostic information for mild cognitive impairment. It also has an increasingly important role in therapeutic trial recruitment and for evaluation of anti-Aβ treatments. Longitudinal observations are required to elucidate the role of Aβ deposition in the course of Alzheimer disease and provide information needed to fully use the prognostic power of this investigation.
DOI: 10.1016/j.mcna.2012.12.017
Journal: The Medical clinics of North America
Type: Journal Article
Subjects: Aged
Alzheimer Disease.genetics.pathology.radionuclide imaging
Amyloid beta-Peptides.analysis.genetics
Aniline Compounds.diagnostic use
Asymptomatic Diseases
Brain.pathology.radionuclide imaging
Carbon Radioisotopes.diagnostic use
Chromosome Aberrations
DNA Mutational Analysis
Diagnosis, Differential
Disease Progression
Fluorine Radioisotopes.diagnostic use
Heterozygote Detection
Mild Cognitive Impairment.genetics.pathology.radionuclide imaging
Positron-Emission Tomography
Statistics as Topic
Thiazoles.diagnostic use
Appears in Collections:Journal articles

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