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Title: | Amyloid imaging with PET in early Alzheimer disease diagnosis. | Austin Authors: | Rowe, Christopher C ;Villemagne, Victor L | Affiliation: | Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia University of Melbourne, Austin Health, Heidelberg, Victoria, Australia |
Issue Date: | 1-May-2013 | Publication information: | The Medical Clinics of North America; 97(3): 377-98 | Abstract: | In vivo imaging of amyloid-β (Aβ) with positron emission tomography has moved from the research arena into clinical practice. Clinicians working with cognitive decline and dementia must become familiar with its benefits and limitations. Amyloid imaging allows earlier diagnosis of Alzheimer disease and better differential diagnosis of dementia and provides prognostic information for mild cognitive impairment. It also has an increasingly important role in therapeutic trial recruitment and for evaluation of anti-Aβ treatments. Longitudinal observations are required to elucidate the role of Aβ deposition in the course of Alzheimer disease and provide information needed to fully use the prognostic power of this investigation. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/11759 | DOI: | 10.1016/j.mcna.2012.12.017 | Journal: | The Medical clinics of North America | URL: | https://pubmed.ncbi.nlm.nih.gov/23642577 | Type: | Journal Article | Subjects: | Aged Alzheimer Disease.genetics.pathology.radionuclide imaging Amyloid beta-Peptides.analysis.genetics Aniline Compounds.diagnostic use Asymptomatic Diseases Brain.pathology.radionuclide imaging Carbon Radioisotopes.diagnostic use Chromosome Aberrations DNA Mutational Analysis Diagnosis, Differential Disease Progression Fluorine Radioisotopes.diagnostic use Heterozygote Detection Humans Mild Cognitive Impairment.genetics.pathology.radionuclide imaging Positron-Emission Tomography Prognosis Statistics as Topic Thiazoles.diagnostic use |
Appears in Collections: | Journal articles |
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