Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11681
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dc.contributor.authorHowell, Jessicaen
dc.contributor.authorAngus, Peter Wen
dc.contributor.authorGow, Paul Jen
dc.contributor.authorVisvanathan, Kumaren
dc.date.accessioned2015-05-16T01:17:56Z
dc.date.available2015-05-16T01:17:56Z
dc.date.issued2013-05-01en
dc.identifier.citationJournal of Gastroenterology and Hepatology; 28(5): 766-76en
dc.identifier.govdoc23432473en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/11681en
dc.description.abstractHepatitis C virus (HCV) infection is a significant global health problem, affecting over 150 million people worldwide. While the critical role of the adaptive immune system in HCV infection is well-established, the importance of the innate immune system in HCV infection has only been recognized in more recent years. Toll-like receptors form the cornerstone of the innate immune response, and there is considerable evidence for their crucial role in hepatitis C infection. This review outlines recent advances made in our understanding of the role of Toll-like receptor function in HCV infection, exploring how HCV manipulates host immunity to evade immune clearance and establish persistent infection despite leading to inflammatory hepatic damage.en
dc.language.isoenen
dc.subject.otherAdaptive Immunity.immunologyen
dc.subject.otherChemokines.metabolismen
dc.subject.otherCytokines.metabolismen
dc.subject.otherDendritic Cells.immunologyen
dc.subject.otherHepatitis C.immunology.therapyen
dc.subject.otherHumansen
dc.subject.otherImmunity, Innate.immunologyen
dc.subject.otherInflammation Mediators.metabolismen
dc.subject.otherLigandsen
dc.subject.otherLiver.immunologyen
dc.subject.otherMolecular Targeted Therapyen
dc.subject.otherSignal Transduction.immunologyen
dc.subject.otherToll-Like Receptors.chemistry.immunology.physiologyen
dc.titleToll-like receptors in hepatitis C infection: implications for pathogenesis and treatment.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Gastroenterology and Hepatologyen
dc.identifier.affiliationLiver Transplant Unit, Austin Hospital, Victoria, Australiaen
dc.identifier.doi10.1111/jgh.12170en
dc.description.pages766-76en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/23432473en
dc.type.austinJournal Articleen
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.deptVictorian Liver Transplant Unit-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptVictorian Liver Transplant Unit-
crisitem.author.deptGastroenterology and Hepatology-
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