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Title
Cortical excitability and refractory epilepsy: a three-year longitudinal transcranial magnetic stimulation study.
Publication Date
2012-12-03
Author(s)
Badawy, Radwa A B
Jackson, Graeme D
Berkovic, Samuel F
Macdonell, Richard A L
Type of document
Journal Article
DOI
10.1142/S012906571250030X
Abstract
Transcranial magnetic stimulation was used to study the effect of recurrent seizures on cortical excitability over time in epilepsy. 77 patients with firm diagnoses of idiopathic generalized epilepsy (IGE) or focal epilepsy were repeatedly evaluated over three years. At onset, all groups had increased cortical excitability. At the end of follow-up the refractory group was associated with a broad increase in cortical excitability. Conversely, cortical excitability decreased in all seizure free groups after introduction of an effective medication.
Link
Citation
International Journal of Neural Systems 2012; 23(1): 1250030
Jornal Title
International journal of neural systems

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