Austin Health

Title
Faecal microbiota transplantation for severe Clostridium difficile infection in the intensive care unit.
Publication Date
2013-02-01
Author(s)
Trubiano, Jason
Gardiner, Bradley
Kwong, Jason C
Ward, Peter
Testro, Adam G
Charles, Patrick G P
Type of document
Journal Article
OrcId
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DOI
10.1097/MEG.0b013e32835b2da9
Abstract
We describe a case of faecal microbiota transplantation (FMT) used for severe binary toxin-positive Clostridium difficile infection in an intensive care setting. The patient was admitted to the ICU of a tertiary hospital and failed traditional maximal pharmacological management. Adjunctive therapy with FMT given through gastroscopy resulted in resolution of the C. difficile-related symptoms. Although there is a growing experience with FMT for recurrent C. difficile infection, published evidence in severe disease is very limited. In a landscape of increasingly severe C. difficile infection, adjunctive FMT may be considered a useful early treatment option.
Link
Citation
European Journal of Gastroenterology and Hepatology; 25(2): 255-7
Jornal Title
European Journal of Gastroenterology and Hepatology

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