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Title: An unusual presentation of herpes simplex virus encephalitis.
Austin Authors: Boyapati, Ray;Papadopoulos, George;Olver, James S ;Geluk, Michael;Johnson, Paul D R 
Affiliation: Department of Medicine, Austin Health, Studley Road, Heidelberg, VIC 3084, Australia
Issue Date: 6-Sep-2012
Publication information: Case Reports in Medicine 2012; 2012(): 241710
Abstract: We present a case of a 65-year-old man with an acute alteration in mental state that was initially diagnosed as a functional psychiatric condition. After extensive workup, herpes simplex virus type 1 (HSV-1) was detected in the patient's cerebrospinal fluid (CSF) by polymerase chain reaction (PCR), and he responded rapidly to treatment with acyclovir. The case illustrates the importance of actively excluding organic causes in such patients, the need to have a low threshold of suspicion for HSV encephalitis, and the central role of CSF PCR testing for the diagnosis of HSV encephalitis, even in the absence of CSF biochemical abnormalities.
Gov't Doc #: 22991517
DOI: 10.1155/2012/241710
Type: Journal Article
Appears in Collections:Journal articles

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