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Title: Impact of ¹⁸F-FDG-PET in decision making for liver metastectomy of colorectal cancer.
Austin Authors: McLeish, Andrew R;Lee, Sze Ting ;Byrne, Amanda J;Scott, Andrew M 
Affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Melbourne, Victoria, Australia
Issue Date: 7-Jan-2011
Publication information: ANZ Journal of Surgery 2011; 82(1-2): 30-5
Abstract: The ability of (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) to impact on management of patients with recurrent colorectal cancer is high. However, direct impact of FDG-PET on surgical management of patients with potentially resectable hepatic metastases is limited.FDG-PET scans of patients with colorectal cancer at Austin Hospital in a 2-year period were retrospectively evaluated. Data were collected on patient demographics, scan indication and sites of disease pre- and post-PET. Results of standard imaging tests and FDG-PET scans were analysed. The potential impact of FDG-PET on proposed surgical management plans was assessed by an experienced surgeon.There were 585 FDG-PET scans performed on 470 patients (309M : 161F, mean age 61.9 years) with colorectal cancer. Hepatic metastases were identified on standard imaging in 232 (39.7%) patients, and FDG-PET confirmed hepatic metastasis in 203 cases, including 22 cases with new lesions, and clarified presence of disease in 34/37 (92%) cases with equivocal standard imaging. In 54 patients, FDG-PET was performed for disease assessment before hepatic resection. FDG-PET had substantial management plan impact in 36/54 (66.7%) patients.FDG-PET can profoundly impact on the management plan of patients with colorectal cancer who may be suitable for hepatic metastectomy.
Gov't Doc #: 22507492
DOI: 10.1111/j.1445-2197.2010.05601.x
Journal: ANZ Journal of Surgery
Type: Journal Article
Subjects: Aged
Aged, 80 and over
Colorectal Neoplasms.pathology
Decision Support Techniques
Fluorodeoxyglucose F18.diagnostic use
Liver Neoplasms.radionuclide
Middle Aged
Patient Care Planning
Positron-Emission Tomography
Radiopharmaceuticals.diagnostic use
Retrospective Studies
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