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Title: Impact of swine influenza and quarantine measures on patients and households during the H1N1/09 pandemic.
Austin Authors: Teh, Benjamin;Olsen, Karen;Black, Jim;Cheng, Allen C;Aboltins, Craig A;Bull, Kirstin;Johnson, Paul D R ;Grayson, M Lindsay ;Torresi, Joseph 
Affiliation: Department of Infectious Diseases, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 22-Nov-2011
Publication information: Scandinavian Journal of Infectious Diseases 2011; 44(4): 289-96
Abstract: To assess the secondary attack rates (SAR) and impact of the 2009 H1N1 epidemic in Melbourne, Victoria, Australia, and the measures implemented to control household transmission.Patients with polymerase chain reaction-confirmed influenza A and pandemic H1N1 (pH1N1) were identified from hospital and microbiology laboratory records and asked to take part in a retrospective survey. Information obtained included: the constellation of symptoms, contact history, secondary infection, and household information, including adherence and attitudes towards quarantine measures.The overall SAR of pH1N1 index patients was 30.6%, but a significantly lower SAR was noted with oseltamivir treatment (36.6% vs 22.8%, p < 0.05). The greatest reduction in SAR was observed when index patients aged 0-4 y received oseltamivir (83.3% vs 22.2%, p < 0.01). Quarantine was requested of 65.8% of patients and 92.8% self-reported adhering to recommendations. pH1N1 index patients, the number of median days bed-bound is 2.5 days, being unable or too sick to work for a median of 5.0 days, and lost a median of 7.0 days of work for reasons related to an influenza-like illness.The pH1N1 influenza pandemic had a significant clinical impact on households. Public health interventions such as oseltamivir treatment of index cases were beneficial in reducing secondary attack rates, whilst quarantine measures were found to have high rates of self-reported compliance, understanding, and acceptability.
Gov't Doc #: 22106922
DOI: 10.3109/00365548.2011.631572
Type: Journal Article
Subjects: Adolescent
Aged, 80 and over
Child, Preschool
Family Characteristics
Influenza A Virus, H1N1 Subtype.isolation & purification
Influenza, Human.epidemiology.prevention & control.psychology
Middle Aged
Patient Compliance.statistics & numerical data
Quarantine.psychology.statistics & numerical data
Retrospective Studies
Statistics, Nonparametric
Appears in Collections:Journal articles

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