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Title: Brain amyloid imaging.
Austin Authors: Rowe, Christopher C ;Villemagne, Victor L 
Affiliation: Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 14-Sep-2011
Publication information: Journal of Nuclear Medicine: 2011; 52(11): 1733-40
Abstract: Imaging of brain β-amyloid plaques with (18)F-labeled tracers for PET will likely be available in clinical practice to assist the diagnosis of Alzheimer disease (AD). With the rapidly growing prevalence of AD as the population ages, and the increasing emphasis on early diagnosis and treatment, brain amyloid imaging is set to become a widely performed investigation. All physicians reading PET scans will need to know the complex relationship between amyloid and cognitive decline, how to best acquire and display images for detection of amyloid, and how to recognize the patterns of tracer binding in AD and other causes of dementia. This article will provide nuclear medicine physicians with the background knowledge required for understanding this emerging investigation, including its appropriate use, and prepare them for practical training in scan interpretation.
DOI: 10.2967/jnumed.110.076315
Type: Journal Article
Subjects: Aged
Alzheimer Disease.complications.metabolism.pathology.radionuclide imaging
Amyloid beta-Peptides.metabolism
Benzothiazoles.diagnostic use
Brain.metabolism.pathology.radionuclide imaging
Education, Medical
Fluorine Radioisotopes.diagnostic use
Image Interpretation, Computer-Assisted
Mild Cognitive Impairment.complications.radionuclide imaging
Molecular Imaging.methods
Positron-Emission Tomography
Radiopharmaceuticals.diagnostic use
Sensitivity and Specificity
Appears in Collections:Journal articles

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