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Title: Management of side effects of androgen deprivation therapy.
Austin Authors: Grossmann, Mathis ;Zajac, Jeffrey D 
Affiliation: Department of Medicine Austin Health/Northern Health, University of Melbourne, Heidelberg, Victoria 3084, Australia
Issue Date: 1-Sep-2011
Publication information: Endocrinology and Metabolism Clinics of North America; 40(3): 655-71, x
Abstract: Androgen deprivation therapy (ADT) is a major component of the contemporary management of prostate cancer. ADT's use is increasing rapidly. The side effects of this therapy include loss of bone mass and fractures, increase in fat mass, and worsening of insulin resistance, the metabolic syndrome, diabetes and cardiovascular risk, and anemia and loss of muscle. Neuropsychological and sexual symptoms are common. The impact of these side effects is often overlooked or underestimated in decisions about prostate cancer therapy. This review surveys the data relating to the side effects of ADT and provides recommendations regarding their minimization and management.
Gov't Doc #: 21889727
DOI: 10.1016/j.ecl.2011.05.004
Type: Journal Article
Subjects: Androgen Antagonists.adverse effects.therapeutic use
Antineoplastic Agents, Hormonal.adverse effects.therapeutic use
Carcinoma.drug therapy.epidemiology.metabolism.physiopathology
Cardiovascular Physiological Phenomena.drug effects
Dietary Supplements.utilization
Drug-Related Side Effects and Adverse Reactions.epidemiology.therapy
Life Style
Prostatic Neoplasms.drug therapy.epidemiology.metabolism.physiopathology
Appears in Collections:Journal articles

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