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Title: | Liver transplantation rapidly stops cerebral ammonia uptake in fulminant hepatic failure. | Austin Authors: | Glassford, Neil J;Farley, K J;Warrillow, Stephen J ;Bellomo, Rinaldo | Affiliation: | Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia | Issue Date: | 1-Jun-2011 | Publication information: | Critical Care and Resuscitation; 13(2): 113-8 | Abstract: | This report describes the effect of liver transplantation on transcerebral ammonia uptake in a case of fulminant hepatic failure. A young woman with fulminant hepatic failure and coma received monitoring of transcerebral ammonia uptake before and after orthotopic liver transplantation. Before liver transplantation, median transcerebral ammonia uptake was 8 µmol/L. After liver transplantation, ammonia uptake decreased to 0 µmol/L. Fulminant hepatic failure is associated with transcerebral ammonia uptake, which is fully and rapidly corrected by liver transplantation. | Gov't Doc #: | 21627580 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/11277 | Journal: | Critical Care and Resuscitation | URL: | https://pubmed.ncbi.nlm.nih.gov/21627580 | Type: | Journal Article | Subjects: | Adult Ammonia.metabolism Brain.metabolism Female Follow-Up Studies Hepatic Encephalopathy.etiology.metabolism.surgery Humans Liver Failure, Acute.complications.metabolism.surgery Liver Transplantation.methods |
Appears in Collections: | Journal articles |
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