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https://ahro.austin.org.au/austinjspui/handle/1/10945| Title: | Rapidly progressive glomerulonephritis complicating primary AL amyloidosis and multiple myeloma. | Austin Authors: | Crosthwaite, Amy;Skene, Alison ;Mount, Peter | Affiliation: | Department of Nephrology, Austin Health, Heidelberg, Victoria, Australia | Issue Date: | 29-Dec-2009 | Publication information: | Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association 2009; 25(8): 2786-9 | Abstract: | Crescentic glomerulonephritis is a rare complication of AA amyloidosis. There are no clinical case reports of this complicating AL amyloidosis. A 67-year-old man developed rapidly progressive glomerulonephritis (RPGN) on a background of primary AL amyloidosis and IgGkappa multiple myeloma. Investigations for causes of glomerulonephritis were negative, and a renal biopsy confirmed crescentic glomerulonephritis and amyloid deposition. He progressed to end stage kidney disease (ESKD) requiring dialysis after 2 months and died 7 months after diagnosis after further treatment of multiple myeloma failed to arrest progression. We believe this to be the first clinical case report of RPGN complicating primary (AL) renal amyloidosis and multiple myeloma. | Gov't Doc #: | 20042399 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/10945 | DOI: | 10.1093/ndt/gfp715 | Journal: | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | URL: | https://pubmed.ncbi.nlm.nih.gov/20042399 | Type: | Journal Article | Subjects: | Aged Amyloid.metabolism Amyloidosis.complications Biopsy Disease Progression Fatal Outcome Glomerulonephritis.diagnosis.etiology Humans Kidney.metabolism.pathology Kidney Failure, Chronic.mortality.therapy Male Multiple Myeloma.complications Renal Dialysis |
| Appears in Collections: | Journal articles |
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