Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/10905
Title: | Dexamethasone-induced flares of Trichophyton rubrum masquerading as docetaxel cutaneous toxicity: a case report. | Austin Authors: | Azad, Arun A;Kaufman, Melissa;Jayarajan, Jyotsna | Affiliation: | Ludwig Institute for Cancer Research, University of Melbourne, Austin Hospital, Austin Health, 145-163 Studley Road, Heidelberg, Victoria, Australia, 3084. | Issue Date: | 23-Jul-2009 | Publication information: | Cases Journal 2009; 2(): 8552 | Abstract: | Docetaxel chemotherapy is increasingly used in the treatment of castration-resistant prostate cancer. Cutaneous toxicity is common with docetaxel, occurring in up to 75% of cases. We present an unusual case of castration-resistant prostate cancer in which our patient developed recurrent but transient episodes of skin rash following each cycle of docetaxel. Initially, the rash was attributed to docetaxel cutaneous toxicity however a microbiological diagnosis of Trichophyton rubrum was subsequently made. We postulated that dexamethasone pre-medication transiently suppressed anti-fungal immunity, and indeed further flares were prevented by significantly reducing the dose of dexamethasone while continuing treatment with docetaxel. | Gov't Doc #: | 19830081 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/10905 | DOI: | 10.4076/1757-1626-2-8552 | Journal: | Cases journal | URL: | https://pubmed.ncbi.nlm.nih.gov/19830081 | Type: | Journal Article |
Appears in Collections: | Journal articles |
Show full item record
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.