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Title: Primary anaplastic pilocytic astrocytoma.
Austin Authors: Azad, Arun A;Deb, Siddhartha;Cher, Lawrence M 
Affiliation: Ludwig Institute Oncology Unit, Level 6, Harold Stokes Building, Austin Hospital, 145-163 Studley Road, Heidelberg, Victoria 3084, Australia
Issue Date: 7-Oct-2009
Publication information: Journal of Clinical Neuroscience 2009; 16(12): 1704-6
Abstract: We report two adult patients with pilocytic astrocytomas with anaplastic features at initial diagnosis. Pilocytic astrocytomas are low-grade astrocytomas that occur rarely in adults. Initial presentation of a pilocytic astrocytoma with anaplastic features is particularly uncommon and making a definitive diagnosis of pilocytic astrocytoma with anaplastic features can be challenging. It is critical to differentiate glioblastoma (World Health Organization [WHO] grade 4) and pilocytic astrocytoma with anaplastic features (WHO grade 3) from pilocytic astrocytoma (WHO grade 1) as there are significant therapeutic and prognostic implications. Improved therapeutic strategies are required for pilocytic astrocytomas with anaplastic features.
Gov't Doc #: 19815416
DOI: 10.1016/j.jocn.2009.04.012
Journal: Journal of Clinical Neuroscience
Type: Journal Article
Subjects: Anaplasia.complications
Brain Neoplasms.complications
Magnetic Resonance Imaging.methods
Middle Aged
Nystagmus, Pathologic.etiology
Appears in Collections:Journal articles

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