Austin Health

Title
18F-FDG-PET imaging of a benign neurofibroma masquerading as metastatic oesophageal carcinoma.
Publication Date
2009-03-19
Author(s)
Azad, Arun A
Chong, Geoffrey
Tauro, A
Aly, Ahmad
Tebbutt, Niall C
Type of document
Journal Article
DOI
10.1007/s12032-009-9196-x
Abstract
We present the case of a 65-year-old male with squamous cell carcinoma of the thoracic oesophagus on a background of neurofibromatosis type 1. On computed tomography, he was noted to have a large left-sided superior mediastinal mass. Initially, this mass was thought to be metastatic lymphadenopathy; however, it did not display fluorodeoxyglucose uptake on positron emission tomography. Subsequent biopsy confirmed the mass to be a neurofibroma and the patient commenced definitive chemo-radiation. Positron emission tomography had a major impact on management since the presumed lymph node disease was not included in the radiation field. In addition, positron emission tomography altered prognostic stratification since lymph node involvement is a poor prognostic factor in oesophageal cancer. We could only identify one other case in the English literature in which positron emission tomography was used to distinguish metastatic carcinoma from a neurofibroma, although there are a number of reports that describe the utility of positron emission tomography in differentiating benign neurofibromas from malignant connective tissue tumours.
Link
Citation
Medical Oncology (northwood, London, England) 2009; 27(2): 230-2
Jornal Title
Medical oncology (Northwood, London, England)

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