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Title: Thrombus entrapped in a patent foramen ovale: a potential source of pulmonary and systemic embolism.
Austin Authors: Kearney, Leighton G ;Srivastava, Piyush M 
Affiliation: Department of Cardiology, Austin Health, Level 5 North Austin Tower, 145 Studley Road, Heidelberg, Victoria 3084, Australia
Issue Date: 27-Feb-2009
Publication information: Heart, Lung & Circulation 2009; 19(1): 58-60
Abstract: Patent foramen ovale (PFO) occurs in up to 30% of the population, making it the most common site for intra-cardiac shunting. The passage of thrombus across a PFO is typically transient, thus is rarely proven. We describe a rare case of a 79-year-old man with thrombus entrapped across a PFO providing a source for ongoing pulmonary and systemic thromboembolism, despite systemic anticoagulation. There is a paucity of literature to guide primary management of this condition. Management options include surgical thrombectomy with PFO closure, thrombolysis and systemic anticoagulation. The role of percutaneous PFO closure devices for secondary prevention of thromboembolic complications is currently under investigation.
Gov't Doc #: 19250868
DOI: 10.1016/j.hlc.2008.12.003
Type: Journal Article
Subjects: Aged
Anticoagulants.therapeutic use
Atrial Appendage.pathology
Atrial Fibrillation.etiology
Atrial Septum.pathology.ultrasonography
Echocardiography, Transesophageal
Embolism.diagnosis.drug therapy.etiology
Fatal Outcome
Foramen Ovale, Patent.complications.diagnosis.drug therapy
Heart Aneurysm.complications.ultrasonography
Heart Diseases.complications.diagnosis.drug therapy
Heparin.therapeutic use
Pulmonary Embolism.diagnosis.drug therapy.etiology
Respiratory Insufficiency.etiology
Shock, Cardiogenic.etiology
Sodium Potassium Chloride Symporter Inhibitors.therapeutic use
Thrombosis.complications.diagnosis.drug therapy
Tomography, X-Ray Computed
Appears in Collections:Journal articles

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