Please use this identifier to cite or link to this item:
Title: The role of abdominal resectional surgery in metastatic melanoma.
Austin Authors: Hodgson, Russell;Fink, Michael A ;Jones, Robert M 
Affiliation: Department of Surgery, University of Melburn, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 1-Oct-2007
Publication information: ANZ Journal of Surgery; 77(10): 855-9
Abstract: We reviewed our experience to determine the role of resectional surgery in metastatic melanoma to the abdomen.An observational study of 25 patients at the Austin Hospital, Melbourne from 1997 to 2005.The median survival after abdominal resectional surgery was 8.3 (range 0.4-41.1) months. Fourteen patients who underwent resection with curative intent (extra-abdominal disease controlled and complete macroscopic clearance of abdominal disease) had improved survival compared with 11 patients who underwent palliative resection (12 month survival, 89 vs 10%, respectively, P < 0.0001). Survival was also superior in patients with up to two metastases compared with more than two (P = 0.0001) and in patients with serum albumin of at least 35 g/L (P = 0.0031). Intent of surgery (curative vs palliative) was the only factor significant on multivariate analysis (P = 0.001). Of patients with preoperative symptoms, 87% had resolution of these symptoms. Operative morbidity was 12%, and 30-day mortality was 4%.In a highly selected group of patients with intra-abdominal melanoma metastases, resection of intra-abdominal metastases with curative intent resulted in prolonged survival compared with patients who underwent palliative resection. Those who underwent palliative resection had good relief of symptoms with minimal morbidity.
Gov't Doc #: 17803548
DOI: 10.1111/j.1445-2197.2007.04258.x
Type: Journal Article
Subjects: Abdominal
Aged, 80 and over
Follow-Up Studies
Middle Aged
Neoplasm Metastasis
Regression Analysis
Retrospective Studies
Survival Analysis
Time Factors
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on Dec 8, 2022

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.