Prevalence of occult metastatic disease in patients undergoing 18F-FDG PET for primary diagnosis or staging of lung carcinoma and solitary pulmonary nodules.

2007-05-21

Lee, S T

Berlangieri, Salvatore U

Poon, A M T

Mitchell, Paul L R

Pathmaraj, K

Tabone, K

Byrne, Amanda J

O'Keefe, Graeme J

Knight, Simon R

Clarke, C Peter

Scott, Andrew M

Journal Article

10.1111/j.1445-5994.2007.01383.x

Accurate staging of lung cancer is essential in determining the most appropriate management plan, as detection of occult metastasis can significantly alter management.The aims of this study are to determine the prevalence of occult metastasis in patients undergoing 2-(18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography (PET) for evaluation of suspected/proven lung carcinoma and correlate pre-PET TNM stage with prevalence of metastasis.FDG-PET, which identified patients with metastasis on institutional database, was re-evaluated by a nuclear medicine physician blinded to clinical information. The confidence level of metastasis was scored on a 5-point scale, with a score of >/=4 considered positive.There were 67 of 645 (10%) patients identified with suspected occult metastasis on FDG-PET. Twelve patients scoring

link

Internal Medicine Journal 2007; 37(11): 753-9

Internal Medicine Journal