Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10366
Title: Fluid resuscitation and the septic kidney: the evidence.
Austin Authors: Licari, Elisa;Calzavacca, Paolo;Ronco, Claudio;Bellomo, Rinaldo 
Affiliation: Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia
Issue Date: 2007
Publication information: Contributions To Nephrology; 156(): 167-77
Abstract: Acute kidney injury (AKI) is a common complication of severe sepsis. Severe sepsis is the most common cause of AKI in ICU. The widely accepted and practiced initial cornerstone of treatment for septic AKI is fluid resuscitation. The biological rationale for fluid resuscitation in septic AKI is based on the assumption that septic AKI is an ischemic form of AKI and that increasing renal perfusion and oxygen delivery by means of fluid resuscitation will protect the kidney. Whether this is true, however, remains uncertain. In this paper, we discuss salient pathophysiological aspects of AKI, review the evidence available on the need for fluid resuscitation, the amount and the type of fluid that might be best suited to AKI and discuss all major aspects of fluid resuscitation for septic AKI in humans and experimental animals.
Gov't Doc #: 17464124
URI: http://ahro.austin.org.au/austinjspui/handle/1/10366
DOI: 10.1159/0000102080
URL: https://pubmed.ncbi.nlm.nih.gov/17464124
Type: Journal Article
Subjects: Acute Kidney Injury.etiology.microbiology.therapy
Animals
Critical Care.methods
Disease Models, Animal
Dogs
Fluid Therapy.methods
Humans
Kidney.blood supply.physiopathology
Regional Blood Flow.physiology
Resuscitation.methods
Sepsis.complications.physiopathology
Swine
Appears in Collections:Journal articles

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