Please use this identifier to cite or link to this item:
Title: Postoperative changes in prothrombin time following hepatic resection: implications for perioperative analgesia.
Austin Authors: Weinberg, Laurence ;Scurrah, N ;Gunning, K;McNicol, Larry
Affiliation: Department of Anaesthesia, Austin Health, Victoria, Australia
Issue Date: 1-Aug-2006
Publication information: Anaesthesia and Intensive Care; 34(4): 438-43
Abstract: Disorders of coagulation may occur after uncomplicated hepatic resection in patients who have normal preoperative coagulation profiles and liver function tests. We present a retrospective study performed in a tertiary care university teaching hospital examining changes in liver function tests and coagulation profiles in patients undergoing hepatic resection. Data were obtained for 124 patients. When compared to the preoperative values, prothrombin times were significantly increased throughout the postoperative period. Prolongation of the prothrombin time was related to both duration of surgery and hepatic resection weight. There was no relationship between prothrombin time and patient age. Disorders of coagulation occur after hepatic resection even in patients who have normal preoperative coagulation and liver function tests. This has implications for anaesthetic practice, particularly when considering the use of an indwelling epidural catheter in patients undergoing hepatic resection.
Gov't Doc #: 16913338
Journal: Anaesthesia and Intensive Care
Type: Journal Article
Subjects: Analgesia
Anesthesia, General
Blood Coagulation Disorders.epidemiology.etiology
Liver Function Tests
Middle Aged
Pain, Postoperative.drug therapy
Postoperative Complications.blood.epidemiology
Prothrombin Time
Retrospective Studies
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on May 19, 2024

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.