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https://ahro.austin.org.au/austinjspui/handle/1/10184| Title: | Validation of a solid-phase extraction high-performance liquid chromatographic assay for doxazosin. | Austin Authors: | Jackman, G P;Colagrande, F;Louis, William J | Affiliation: | Department of Clinical Pharmacology and Therapeutics, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 3-May-1991 | Publication information: | Journal of Chromatography; 566(1): 234-8 | Abstract: | The determination of doxazosin by high-performance liquid chromatography with fluorescence detection is described. Propanolol was used as the internal standard. Plasma samples were treated with methanol to precipitate the proteins. Doxazosin was isolated with C18 reversed-phase extraction columns. The determination limit is 1 ng/ml of plasma, while the extraction columns can be reused frequently. The method is applied to clinical trial samples. | Gov't Doc #: | 1679435 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/10184 | Journal: | Journal of chromatography | URL: | https://pubmed.ncbi.nlm.nih.gov/1679435 | Type: | Journal Article | Subjects: | Adrenergic alpha-Antagonists.blood Chromatography, High Pressure Liquid.methods.standards.statistics & numerical data Doxazosin Humans Hydrogen-Ion Concentration Methanol Prazosin.analogs & derivatives.blood Propranolol |
| Appears in Collections: | Journal articles |
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