Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/18931
Title: Age 80 years and over is not associated with increased morbidity and mortality following pancreaticoduodenectomy.
Authors: Kim, Sandy Y;Fink, Michael A;Perini, Marcos V;Houli, Nezor;Weinberg, Laurence;Muralidharan, Vijayaragavan;Starkey, Graham M;Jones, Robert M;Christophi, Christopher;Nikfarjam, Mehrdad
Affiliation: Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
Issue Date: May-2018
EDate: 2017-06-07
Citation: ANZ journal of surgery 2018; 88(5): E445-E450
Abstract: Pancreaticoduodenectomy (PD) is associated with high morbidity, which is perceived to be increased in the elderly. To our knowledge there have been no Australian series that have compared outcomes of patients over the age of 80 undergoing PD to those who are younger. Patients who underwent PD between January 2008 and November 2015 were identified from a prospectively maintained database. A total of 165 patients underwent PD of whom 17 (10.3%) were aged 80 or over. The pre-operative health status, according to American Society of Anesthesiologists class was similar between the groups (P = 0.420). The 90-day mortality rates (5.9% in the elderly and 2% in the younger group; P = 0.355) and the post-operative complication rates (64.7% in the elderly versus 62.8% in the younger group; P = 0.88) were similar. Overall median length of hospital stay was also similar between the groups, but older patients were far more likely to be discharged to a rehabilitation facility than younger patients (47.1 versus 12.8%; P < 0.0001). Older patients with pancreatic adenocarcinoma (n = 10) had significantly lower median survival than the younger group (n = 69) (16.6 versus 22.5 months; P = 0.048). No significant differences were seen in the rate of complications following PD in patients aged 80 or over compared to younger patients, although there appears to be a shorter survival in the elderly patients treated for pancreatic cancer. Careful selection of elderly patients and optimal peri-operative care, rather than age should be used to determine whether surgical intervention is indicated in this patient group.
URI: http://ahro.austin.org.au/austinjspui/handle/1/18931
DOI: 10.1111/ans.14039
ORCID: 0000-0003-4866-276X
0000-0002-0165-1564
0000-0001-7403-7680
0000-0001-8247-8937
0000-0003-4866-276X
PubMed URL: 28593708
Type: Journal Article
Subjects: aged 80 or over
octogenarian
pancreas
pancreaticoduodenectomy
post-operative outcome
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.